For binary (safety) data, effect measures were presented as risk ratios (RRs) with corresponding 95% CIs.
The first author (ED) extracted study characteristics (study design, population, intervention(s), comparison(s), and outcome(s)) and study results (descriptive discrete or continuous data, effect measures and effect estimates) using a pre-designed data extraction form.
Quantitative data from the retrieved IPD-NMA (eg, number of patients, studies and treatments in the network) will be summarised by medians and IQRs, and categorical data (eg, effect measure, outcome data type, reference treatment type (eg, placebo, control, active) by frequencies and percentages.
Additionally, no significant differences in age and gender were observed between BCC and SCC cases that completed the study questionnaire and those that did not and further investigations demonstrated no bias due to missing data in the effect measures between patterns and timing of sunlight exposure in NMSC.
The three studies [ 36, 37, 40], reporting the association between mobility and fractures used different definitions and could not be pooled, and Nakamura [ 37] did not provide data to convert the effect measures from HR to RR. Results from these studies were heterogeneous.
Data type, continuous; effect measure, weighted mean difference; analysis model, fixed effects; statistical method, inverse variance.
Data type, dichotomous; effect measure, odds ratio; analysis model, fixed effects; statistical method, Mantel–Haenszel.
To include all relevant data regardless of effect measure chosen, reviewers should also include zero total event trials when calculating pooled estimates using OR and RR.
The typical metric used in recent works (e.g., [6]) has been to measure the effect of big data on the i-th company's added value expansion, (call it, Yi), that is, recent work measuring the big data effect as a productivity effect.
These were used as inputs, along with the drug dose and effect measure data, for the estimation of pharmacodynamic parameters.
We synthesised data on mortality for the donor group (MSD-HSCT) versus the no donor group (IST) by using the HR for time-to-event data as the primary effect measure with a random-effects model.
