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X-ray crystallography, mass spectrometry, and functional data demonstrate that these peptide mimetics are efficient covalent inhibitors of Siah and antagonize Siah-dependent regulation of Erk and Hif signaling in the cell.
Our data demonstrate that these proteolytic maturation events are not required for procapsid assembly or for DNA packaging into the structure, but that proteolysis is essential to late steps in particle assembly and/or in subsequent infection of a host cell.
These data demonstrate that these two antimicrobial peptides have no haemolytic activity near their MICs.
These data demonstrate that these two proteins specifically associate with each other in a protein complex.
Our data demonstrate that these groups influenced the state's genetic substructure.
Our data demonstrate that these two SOFL proteins act redundantly to modulate specific cytokinin levels as well as responsiveness.
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Altogether, these data demonstrate that the CIC ETV5 axis is crucial for regulation of TFH cell differentiation.
Collectively, these data demonstrate that the initial recovery of hindlimb locomotion transpires independently of oligodendrocyte remyelination following thoracic contusive SCI.
These data demonstrate that the NF1 siRNA silencing in fibroblasts results in the cellular phenotype of partial mechanosensoric blindness.
Together, these data demonstrate that the EMT phenotype of stage III PASE develops in a SNAI1-dependent manner.
At least four studies have demonstrated that GR activation affects the DNA binding of NF-κB3,46,-48, althisgh this was not observed in at least three other reports45,49,50, whereas our data demonstrates that these effects are gene selective.
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