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Here, we compared the long-term fingolimod (0.5 mg dose) safety data in the LONGTERMS study (up to data cut-off), with shorter-term (1 2 years) safety data pooled from the randomized controlled trials.
As of the data cut-off date of August 31, 2018, of the 35 patients treated in part 2, 22 completed the study, 7 are ongoing in follow-up, and 1 patient is continuing with study treatment (Fig. 1).
The final data cut-off date was 30 September 2012.
Data cut-off was the June 30 , 2013
Data cut-off for the present interim analysis was March 31 , 2012
At data cut-off, 33% of sunitinib- and 29% of capecitabine-treated patients had died.
As of the data cut-off, 26 of the 27 eligible patients had experienced tumour relapse.
Four of these patients remained on treatment at the time of data cut-off.
Data cut-off for the results presented here was July 10 , 2009
As of the data cut-off, 13 patients (22 %) had died.
An additional data cut-off (February 2012) was made for the PFS and OS evaluation.
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