These technologies provide additional types of data that were previously impossible, or too difficult, to collect, with practical advantages over conventional data collection mechanisms (e.g. lower cost, higher reliability and accuracy).
These data collection mechanisms are invisible to all but the most sophisticated users -- and the tools to opt-out or block them have limited effectiveness.
This inconsistency was attributed to a variety of factors, including differences in data collection mechanisms and product use factors.
In the case of this study, we speculate that the general trend of lower nausea rates in the PLM database compared to those reported in corresponding medication labels is driven largely by differences in data collection mechanisms.
Therefore, any data formats, data collection mechanisms and information processing steps should continue to retain and extend contextual characteristics of aggregated data as it moves vertically from raw state towards its manifestation as complex, serviceable information.
While there are likely many factors driving the discrepancy between these two sources, including differences in data collection mechanisms and product use factors, this study demonstrates a quantifiable relationship in side effect reporting frequencies between sources of real-world evidence and the controlled environment of clinical trials.
