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The process captures the variance in the data collected from trial participants and accounts for any correlations between parameters.
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Missing data is a problem that is ubiquitous to all clinical studies and a source of multiple problems from an analytic point of view (reduced statistical power, increased the type I error, bias) Statistical approaches have been developed to analyze data collected from trials with missing data.
Tsai et al. [48] used cost and outcome data collected from a trial that recruited severely obese individuals who were randomised to a low carbohydrate or standard weight loss program and concluded the novel diet was not cost-effective.
However, they have no access to data collected from the trial or input into the study design, analysis or reporting of the results.
Treatment evaluations will be performed according to the principle of intention-to-treat (ITT), using data collected from individual trial participants at randomised schools.
Assumptions could be made concerning the timing of re-treatment in patients who received dual therapy in SPRINT-2 using data collected from a trial in previously treated patients (RESPOND-2) [ 18].
We therefore conducted a post-hoc analysis using data collected from that trial, in order to explore the factors associated with the better global response of anidulafungin, specifically in patients with C. albicans infections.
After the processing of the results, the comparative analysis of the data collected from the trials in the driving simulator and the trials in the real traffic conditions followed.
Long-term data collected from clinical trials of PID patients treated with gene therapy (the majority of these trials have employed conventional γ-retroviral vectors) have shown clear signs of efficacy with more than 90% of the patients surviving without any serious adverse event (SAE).
Therefore, it is fairly common to expect variability in data collected from digestibility trials with fish.
We analyzed data collected from these trials at about 5-year intervals since their installation.
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