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Averaged linked clustering and data centering was performed with LAD.
Limma packages were used for background correction; a within-array method for data centering followed by a between-array method using quantile normalization.
Similar to the accuracy data, centering the data has an effect on the stability of the HPC algorithm, namely HPC-DEN is more stable for centered data while the HPC-RIA is more stable for the uncentered data.
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