In 2007, only 18 per cent of pregnant women in low- and middle-income countries from which data was available received an HIV test.
Of the 70 trials in this subset, only 27 (39%) made their data available, although they received 1875 of 2761 (68%) aggregate citations.
Even with data available, leaders may receive inaccessible or erroneously reported information due to a lack of real-time reporting, simply because there was too much process in doing so.
However, there are no long-term (>5 years) RFS and OS data available for patients receiving adjuvant chemotherapy, which could influence the results.
Another potential limitation was that we did not have data available to identify participants receiving uric acid lowering drugs at the time of measurement.
*Including 1 total arthroplasty † No data available for 15 patients receiving and 10 patients not receiving acetylsalicylic acid ‡ Defined as creatinine ≥105 μmol/L in males and ≥95 μmol/L in females ASA: American Society of Anesthesiologists; NSAID: non-steroidal anti-inflammatory drugs.
In contrast, however, there were nearly 29,000 deaths involving legal and illegal opioids in 2014 (the latest data available)— and poison centers received more than 40,000 calls related to opioids between January and the end of August 2016 alone.
Weaknesses included absence of information on recurrences and that the information in the clinical register is limited to intended chemo- and hormonal treatment, with no data available on actual treatment received.
The data available on patients who received a cytostatic therapy show that persistent DNA damage in lymphocytes before culture can be expressed as MN during the in-vitro cell proliferation.
It is possible that a relatively large proportion of the patients did not receive combination chemotherapy, but unfortunately, we only had data available on whether a patient received chemotherapy, not on the type or combinations of chemotherapy.
