The method used for genomic data assembly is described in the Materials and methods and summarized in Supplementary Fig. S1 and Table S1.
Contig sequences, obtained from 454 data assembly, are provided in supporting information, Table S1.
The flow chart of data assembly was provided in the Additional file 1.
ML ran the early stage QTL analyses, was responsible for the data assembly, and participated in the growth curve analyses.
The rigorous approach of the data assembly, recursive BLAST, in our analysis excludes the vast majority of sequences from multi-gene families, which are the source of paralogous sequences, from the analysis.
Anonymised and completed SF-36 and NASS questionnaires were scanned to upload by secure data transfer to an independent company (RehabNET AG, Zurich, Switzerland) for data assembly and subsequently returned for in-house analysis.
Anonymised and completed SF-36 and NASS questionnaires were scanned to upload by secure data transfer to an independent company (RehabNET AG, Zürich, Switzerland) for data assembly and subsequently returned for in-house analysis.
RSM developed the study design, was involved in data assembly and interpretation, and drafted the manuscript.
DAP, PDM, WC, SS, GSB compiled and managed the patient database and were involved in data assembly.
Several of the long autocorrelation tracts we observed in our expression data assembly may represent additional cases of aneuploidies in the strains used for generating the data.
