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The proposed statistical method can be modified to other population-based family data ascertained from a disease registry provided that the ascertainment process is well documented, and that external information concerning the sizes of birth cohorts and a suitable reference sample are available.
The aim of this study was to assess similarities and differences between methods of performance comparisons under binary (yes or no) and receiver-operating characteristic (ROC type pseudocontinuous (0 100) rating data ascertained during an observer performance study of interpretation of full-field digital mammography (FFDM) versus FFDM plus digital breast tomosynthesis.
Thus the Perlegen data ascertained 73% of the SNP sites but reported high quality genotypes that differ between WSB and PWD at only 23% of those sites, instead providing ambiguous calls at many sites.
Clinical and laboratory data ascertained longitudinally are expressed as baseline and as average over follow-up.
Primary TKR data ascertained from the Australian Orthopaedic Association National Joint Replacement Registry.
The API study data are derived from data ascertained for the BASIC-HHD study[ 18].
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Analytical data ascertaining nominal concentrations for single exposures and for the mixture are given in Table 1.
Analyses included only patients where data were ascertained (denominator data are provided in tables).
All clinical data was ascertained after reviewing and collecting data from the patient's medical records.
Case data were ascertained from the population-based Northern Congenital Abnormality Survey and control data from national data on all births.
The data were ascertained by retrospectively linking several databases with electronically coded data.
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