Of 123 GPs asked to participate, 53 (43.0%) agreed[ 14] and over the course of data collection (which took one year), 42 contributed as outlined below.
Nevertheless, the major conclusions are not well supported by the data provided, as outlined below: We thank the reviewer for their time and constructive comments on our manuscript.
Nevertheless, the major conclusions are not well supported by the data provided, as outlined below: 1) How accurate is the mass-spec quantification of protein abundance in interphase versus mitosis?
Data were collected on cardiovascular risk factors, physical activity including daily steps, anthropometric parameters and dietary information, as outlined below.
The manuscript has been improved but there are some remaining issues that need to be addressed before acceptance, as outlined below: The data in Figure 5B should be improved.
The manuscript has been improved but there are some remaining issues that need to be addressed, as outlined below: 1) Data are added to show SIGN-R1+ staining of isolated LN macrophages by fluorescence microscopy of sorted cells.
We thank the reviewers for calling our attention to Figure 7, which allowed us to identify a problem in the data reported in the initial submission, as outlined below.
The manuscript has been improved but there are some remaining issues that need to be addressed before acceptance, as outlined below: 1) Data availability: given that this is now being considered as a Tools and resources article, we feel that the data availability section should be more prominent.
The manuscript has been improved but there are some remaining issues that need to be addressed before acceptance, as outlined below: The data regarding the sensitivity of endogenous TGFβ to stiffness of the matrix are interesting and important for the study.
The failure force, elongation, and absorbed energy were compared with previously reported control data [ 19], obtained using the same methodology as outlined below.
