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In addition, the benefit of our approach is that we provide data applicable to synovial samples from patients with different disease durations and different pharmacological treatments, which maximizes differences between patients [ 1], thus increasing the representativeness of our study.

The RMA Hunter tool allows fast RMA correction, and thus, it should be useful when processing large amounts of whole-genome/whole-exome sequencing data, and is especially applicable to samples that remained without a clear diagnosis in massive next-generation sequencing based clinical studies.

It is not clear to what extent our data are applicable to the AVS protocols that do not use adrenal stimulation.

By describing known factors which affect expression estimates this article provides guidelines for appropriate quality control and pre-processing of the data, additionally applicable to other transcriptome analysis methods that utilize similar sample handling protocols.

The proposed JVSS algorithm is applicable to systems that use structured waveforms to represent encoded data.

Any assumptions made by the bioanalyst leading to changes or transformations to the data are also noted in this text header where applicable, to ensure that the data could be clearly traced back to the original form.

To the extent that these data are applicable to humans, the results of the present study provide some experimental evidence that stressful life events may increase the attractiveness of alcohol as an anxiolytic agent for adolescents.

Although the possibility of referral bias can not be excluded it is likely that our data are applicable to all patients with imported malaria requiring admission to ICU.

The minimal differences between the Kaplan-Meir estimates and those from the multivariate models for incubation period strongly support earlier opinions that malariotherapy data are applicable to natural infections (30 ).

By controlling for age and sex and focusing on one mesalazine formulation in isolation, the confounding effects of these variables are minimised, while ensuring that the data remain applicable to real clinical settings.

Apart from the biometric data applicable for discretization, it is important that unnecessary yet sensitive information such as ethnic origin, gender and medical condition should also be protected.

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