Questionnaires were also used to collect information about sociodemographic data, anxiety, pregnancy data and personality.
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The following data were collected: socio-demographic parameters, pTNM stage, clinical data, anxiety (Spielberger trait anxiety inventory) [ 17, 18], depression (self-administered Beck Depression Inventory, BDI) [ 19], and QOL (functional assessment of chronic illness therapy, FACIT) scores [ 20- 22].
For this reason, we did not include anxiety in our analyses, although prevalence data for anxiety were available because about 15% of anxiety is accompanied by depression in Korea.
We collected data on anxiety (state scale of the Spielberger State Trait Anxiety Inventory) (Spielberger et al, 1983), depression (Center for Epidemiologic Studies Depression Scale) (Radloff, 1977), and cancer related distress (Impact of Event Scale) (Horowitz et al, 1979).
Only one study published data on anxiety during triple therapy and found a comparable reported rate of anxiety in patients treated with triple therapy (10%) versus standard therapy alone (12%) [ 4].
The CDFs for the HADS anxiety and depression scores indicate that 52.6% and 50.3% of exenatide BID patients and 52.9% and 48.0% of insulin patients reported no worsening in HADS anxiety and depression scores, respectively, at the 24-month visit (missing data overall: anxiety 19.6%; depression 21.5%).
Data for anxiety, depression and stress were obtained using the shortened version of the Depression, Anxiety and Stress Scale (DASS-21) [ 25].
Although both anxiety and depression were primary outcomes for this review, only two suitable studies included data for anxiety, and there was no effect of psychological treatment on secondary outcomes, such as ADL, quality of life, neuropsychiatric symptoms and cognition, or on caregiver depression.
