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Furthermore, there are some microRNA-specific problems to be solved, such as building consensus on normalization of the microRNA expression data and the specificity of microRNA detection to distinguish microRNAs with high sequence homology.
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In the next sections we will present an alternative computational method which uses all available Chip-seq data and estimates the specificity of Chip-seq assay without (i) assumptions regarding physical distribution non-specific Chip-seq DNA clusters (noise BEs) and (ii) the need for a validation of the results in ChIP-q-PCR assay.
Figure 6 displays the difference of actual specificity (calculated using the training data) and the nominal specificity (predetermined 1 - α) for different values of α.
These experiments concur with the in vitro data and demonstrate the specificity of 89Zr-DFO-trastuzumab for the HER2/neu antigen in vivo.
In the study that had 32 (25%) of 128 prevalence of anti-topo I in SLE [ 8], only four of 32 ELISA positives were double immunodiffusion positive, and data supporting the specificity of ELISA were limited.
The primary differences between the two libraries can be attributed to the relative difference in scale, with not only the level of detail changing, but also number of data layers represented and the specificity of encoding used to attribute individual features.
We analyzed only hospital discharge data and the sensitivity and specificity of hospital discharge coding for CDAD are largely unknown (16, 17 ).
First, we only analyzed hospital discharge data, and the sensitivity and specificity of hospital discharge coding for CDAD are not well known.
We tested electronic automated data extraction of ILI data from routine GP records, assessed compatibility of the adapted software with GP office networks and investigated the timeliness of data and the sensitivity and specificity of automated ILI syndromic surveillance.
Data for the specificity and sensitivity of these criteria in adults are sparse, however, and some studies have shown a high incidence of positive tourniquet test results in patients with laboratory-confirmed influenza (7, 8 ).
CONCLUSIONS: The data highlight the specificity and the sensitivity of the TAB 004 antibody in differentiating normal versus tumor form of MUC1 and its utility as a targeted imaging agent for early detection, tumor monitoring response, as well as potential clinical use for targeted drug delivery.
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