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MJW and ADW wrote the manuscript and reviewed all data and conceived the study with CD.
MA supervised the analysis of methylation data and conceived the KEGG experiment.
JFS, KC, JBL and YLQ analysed and interpreted the data, and conceived the management pathways used.
MC led the analysis of screening registry data and conceived the basic design of the screening model.
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EMR revised critically the first and final draft, participated in the data acquisition, and conceived the design of the study, EAF conceptual and planning of the design of the study, surgical pathology data acquisition and analysis.
YYC participated in data collection and conceived the design.
KB carried out data collection and conceived the study.
MASR participated in data collection and conceived the study.
AC was responsible for the microarray data analysis and conceived the project.
VAK did data analysis and conceived the study, coordinated the project, and wrote the final version of the manuscript.
JPD participated in the design of the study and its coordination, performed microarray data analysis and conceived the manuscript.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com