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Data were analyzed using MacSynergy II (kindly provided by Marc Prichard, University of Alabama at Birmingham (UAB)).
Differential surface plot at the 95% confidence level (CI) were calculated and generated by using MacSynergy II for the drug drug interaction in the right panels.
MTS was analyzed statistically using MacSynergy II software to 95% confidence.
Flow cytometry was carried out with a BD LSR II instrument, with data analysis using FlowJo software (TreeStar).
Data analysis used repeated-measures ANOVA (b,c).
Evaluation of the character of the combined effects was performed according to the three dimensional model of Prichard and Shipman using MacSynergy software [ 10].
From these data, the 50% inhibitory concentration (IC50), was calculated using the MacSynergy II Software [28].
For each condition, we measured at least 2 × 105 events using a LSRII from BD. Data analysis was done using Flowing II.
Data analysis performed using SPSS 19.
Synergy was calculated using the MacSynergy II software developed by Prichard and Shipman, which was modified to accommodate a three-drug combination [12] and is similar to that reported previously describing this approach [13].
Source: Author's analysis using data from RegInfo.gov.
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