Variations in PET camera calibration, image reconstruction, and data analysis and/or settings can have more than a 50% effect on the measured SUV [ 15].
The program STRUCTURE [ 20] was used to predict the minimum number of genetic clusters (K) within the composite data, with analysis settings as previously described [ 14].
After filtering all the variants, obtained with data analysis and filter settings as described in 'Methods', we obtained a list of 171 variants.
Line spectra data were then processed into peak list by data analysis using the following settings.
Single channel Cy3 fluorescence data were extracted using BeadStudio data analysis software with default settings.
Dissimilarities in data sources, clinical care settings, data analysis techniques, and patient characteristics may explain some of the differences in the treatment discontinuation estimates.
Semantic rules linking the above quality attributes in order to support users in selecting the appropriate data, analysis methods and parameter settings for their drug surveillance use case, e.g. the targeted drug(s) or health conditions of interest (to address issue I.3).
Analysis settings for data segmentation and calling were the following: significant threshold for Rank Segmentation algorithm: 0.005, Max Continuous Probe Spacing: 6000, Min number of probes per segment: 6, high level gain: 0.485, gain, 0.138, loss -0.153, homozygous copy loss -0.153
GMM (senior author) designed experimental settings, finalized data analysis and the writing of the manuscript.
DS (corresponding author) instigated the project, designed experimental settings, finalized data analysis and writing of the manuscript.
First, the parameters implemented in the configuration file are currently undergoing sweeps for a wide range of values to determine optimal settings for data analysis.
