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One in five marriages now end in divorce, according to government data, a fourfold increase in the past 15 years.
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The Framingham study data revealed a fourfold greater incidence of congestive heart failure in diabetic men and an eightfold increase in diabetic women, compared with nondiabetic subjects (8).
The data generated show that a fourfold reduction in the radiological and integrated thermal output is achievable in single recycle using IMF, as compared to direct disposal of an energy equivalent spent UOX.
Data were expressed in a fourfold table containing concordant and discordant pairs.
Between 1978 and 2007, Denmark experienced a two- and threefold increase in SCC incidence in males and females, respectively 7. Data from Sweden showed a fourfold increase in the SCC incidence rate in both sexes from 1960 to 2004 8.
Nevertheless, our data show that despite a fourfold lower total HSL protein content in muscle of type 2 diabetic men, total HSL serine 660 phosphorylation and the ratio of phosphorylated HSL serine 660 to total HSL was significantly higher at baseline in type 2 diabetic men compared with controls.
Extant data fit the confirmed case definition of a fourfold rise in indirect immunofluorescence assay (IFA) titer or a single titer of >1 128 with clinical symptoms.
Analysis of SQSTM1 revealed a strong accumulation of the protein in tumors (Fig. 2b) a fourfold increase (densitometric mean value; data not shown), which is indicative of an impairment of autophagic degradation.
One clone, showing a fourfold induction in response to tetracycline removal (data not shown), was used for subsequent gene trapping.
Our data, similarly, showed that subjects with BMIs ≥ 30 had a fourfold higher prevalence of DM than subjects with BMIs of 20 to 24.
Pharmacokinetic parameters were variable, spanning a fourfold range of values, consistent with previous published data [6].
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