Since a linear increase in the resolution of image data entails a cubic increase in data size, it is mandatory to devote considerable attention to adequate archiving and computation systems as well as to advanced software for the purpose of 3D visualization and interactive viewing.
We also analysed the data through a cubic regression model, as often suggested for human genome data [ 5], but obtained unrealistic copy number distributions (results not shown).
The update rule was obtained by fitting the Figure 4B data to a cubic equation with a least square method.
Empirical investigation of the raw data suggested a cubic effect for age at death on the log-odds of discontinuation of dialysis.
The parent fraction was modelled using a sigmoid function, the plasma over blood ratio using an exponential approach to a constant (only the first 10 min), and the whole series of plasma and blood data points using a cubic spline interpolation, see Appendix.
Chemical baselines were removed prior to data fitting, using a cubic baseline routine (manufacturer's software).
Using available data, we fitted a cubic curve of log-transformed population for 1 year to estimate Utah's population for other years.
For example, a given pair of signals corresponding to measurements for one sequence (e.g., a gene) can be compared statistically by computing the variance for each signal using the function derived from the fitted data (e.g., a cubic polynomial in Fig. 5).
To consider the statistical distribution, pentad rainfall data were normalized by a cubic root and then standardized for the analysis.
Array data were fit to a cubic spline normalization model in GenomeStudio, and the expressed gene targets were identified using a detection level ≥0.95.
