Sentence examples for dat reduction from inspiring English sources

The analysis of striatal DAT levels using SPECT and DAT immunohistochemistry yielded highly comparable results on the percentage of DAT reduction in each MPTP group.

Our primary objective was to describe the pattern of DAT reduction in CBS compared to PD and healthy control subjects and to correlate DAT binding with clinical features.

As we and others have previously shown, DAT reduction estimated in vivo by SPECT is lower compared with ex vivo quantification of dopaminergic cell bodies or terminals [33], [34].

36 The magnitude of DA and DAT reductions in caudate (2.5% and 17.5% of controls, respectively) is greater in our study compared to two other studies, which observed reductions in DA and DAT markers in caudate ranging from 9% to 30% of controls, and more pronounced reductions (2 3% of controls) in putamen.

This is consistent with the usual DaT concentration reduction rate, which is faster in the early stages of the disease than in the later stages [28] but can prevent the index from correctly following the disease progression as measured by other clinical features.

There were no differences in DAT uptake reduction rates between PD and PSP.

Similarly, mice with a permanent reduction of DAT functioning (DAT knockdown) exhibited increased preference for riskier options in the mouse Iowa gambling task (IGT; [ 71]).

The treatment of σ1R+/− mice with PRE084 or the administration of NMDA in σ1R−/− mice could correct the reduction in DAT mRNA (P<0.01, n=8) and DAT protein (P<0.01, n=8).

However, pramipexole treatment reduced DAT-IR of DA fibers 7 days post-treatment, suggesting a reduction in DAT sites.

Cell culture work has shown that acute AMPH application results in rapid trafficking of DATs to the membrane (in less than 1 min), while continuous exposure results in a subsequent reduction in DAT surface expression that falls below predrug levels.

Visually, this study looks normal, although a mild reduction in DAT binding is seen in the left posterior putamen and possibly on the right posterior putamen as seen in the ACSC reconstruction.