Sentence examples for danger sequence from inspiring English sources

For this purpose we utilized the pairwise alignments between the psi-BLAST-generated Mab-21 profile and each DANGER sequence.

A unique DANGER sequence from the unicellular choanoflagellate species Monosiga ovata assumes an outgroup position (Figure 1A and Figure S2).

We found that DANGER sequences are differentially expressed in several tissues at various developmental stages (Figure S13) suggesting functional divergence between paralogous DANGER sequences.

This analysis shows the Mab-21 domain sequence is highly divergent among the paralogous DANGER sequences.

This is supported by the existence of at least one DANGER homolog in choanoflagellates and the apparent absence of DANGER sequences in other eukaryotic kingdoms.

In order to compare these alignments, all DANGER sequences were mapped onto the Mab-21 profile sequence according to the pairwise alignment coordinates.

To gain insight into the evolutionary processes that shaped the DANGER sequences, we examined the location of the indels within the Mab-21 domain sequence.

Genetic distances produced by several independent methods (data not shown) and the multiple sequence alignment (Figure S3) further demonstrate the divergence of paralogous DANGER sequences.

Annotated genomic regions for the human, mouse, zebrafish, fly and nematode DANGER sequences were collected from the NCBI and Ensembl databases.

Notably, this species contains multiple DANGER sequences which cluster with different DANGER families, indicating that the DANGER superfamily was expanded and already diversified in the cnidarian-bilaterian ancestor (Figure 1A and Figure S2).

Coupling the aforementioned observations with the presence of introns at the C-terminus of microdomain I sequences (Figure 2B), we hypothesize that DANGER sequences have acquired microdomain I through exon-shuffling [17] early in vertebrate evolution.