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The findings of dampening effects on cell activation provided by the HLA-DR protein and its binding to cell surface molecules other than CD4 and TCR substantially extends the understanding of the regulation of the immune activation process and the interactions involved.
Hormone replacement therapy (HRT) has been proposed as a target for treatment and prevention in AD because of dampening effects on Aβ demonstrated in preclinical studies [ 20, 21].
We also observed dampening effects on TNF-alpha concomitant with dramatic increases in IL-4 production in the serum after peptides treatment, which was relevant to inhibiting arthritic progression.
Although operating at such high rates to mimic cell swimming velocities may result in the cantilevers being subject to hydraulic dampening, we maintained consistent experimental conditions (including solution viscosity) throughout the experiments, thus any potential hydraulic dampening effects are consistent across the three surfaces investigated here.
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"We saw no dampening effect on the caseload," the document said.
When the market does turn down, it will have the usual dampening effect on economic growth.
The climate of fear in the Clinton White House exerted, without doubt, a dampening effect on the Administration's internal dialogue.
And even the threat of a shutdown already is probably having a dampening effect on our economy.
But austerity is still having a dampening effect on the economy, and is making it harder for the chancellor to hit his deficit reduction targets.
Dissent is likely to be heightened this time, without the dampening effect of a coalition, and in the fever of an EU referendum debate.
Some might think this puts a dampening effect on an already very sombre story, but I find it a change from the usual, helpless feminine characters.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com