Sentence examples for dampen the function of from inspiring English sources

Drugs such as cyclosporine A, NSAIDs, and drugs that modulate multiple sclerosis and arthritis could all be considered as immune cell modulators that could also act to dampen the function of activated Kupffer cells and the resultant expression of paracrine cytokines.

Furthermore, overexpression of a single HTLV-1 gene (tax) was capable of reducing Foxp3 expression and dampening the suppressive function of healthy donor CD4+CD25+ T cells [20].

Furthermore, we have shown the dampening of the function of β-catenin in the absence of Tcf3 still influences pluripotency and that this effect is likely to be associated with the β-catenin/Oct4 interaction.

Our screening results indicate that growth factors [74], protein kinase A, and protein kinase C [75] [77] signaling cascades that dampen the formation and/or function of gap junctions also induce SREBP activity.

Additionally, the IFN γ produced by activated lymphocytes at the tumor site induces the expression of immunomodulatory molecules that dampen the immune response and inhibit the function of antitumor CTL.

The diversity stability hypothesis states that current losses of biodiversity can impair the ability of an ecosystem to dampen the effect of environmental perturbations on its functioning.

However, this immune regulation can counteract the function of CD4+ or CD8+ effector T cells and paradoxically dampen the control of infection.

Enhancement of IL-10 signaling in T cells may regulate the function of Tregs, which can dampen the harmful autoimmune responses.

Whereas the acute activation of this response likely serves beneficial functions, we hypothesize that repeated induction of this depot specific response may dampen the ability of non-visceral adipose tissue to absorb, retain lipids and/or expand via hyperplasia.

IL-10 signaling in T cells is critical for dampening the pathogenesis of collagen-induced arthritis by maintaining the function of Tregs and the recruitment of IL-17+γδ T cells.

It did not seem to dampen the spirit of fans.