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But it, too, seemed to dampen the activity only of T cells that were being activated, like those attacking the insulin-producing cells, said Dr. Bluestone, who developed the drug.
Sun exposure tends to dampen the activity of immune cells in the skin and has an anti-inflammatory effect, which is why people with eczema and psoriasis often notice an improvement during the summer months.
The protein sits on the surface of T cells and helps dampen the activity of the cells after an immune response, but tumors have found ways to hide from T cell attack by flipping on the PD-1 switch themselves.
A more feasible approach to dampen the activity of lymphocytes in RA is the inhibition of ICAM-1.
We speculate here that these stresses may dampen the activity of enzymes that protect against oxidative stress, such as SOD2 and IDH2, via direct acetylation [ 29, 54, 55].
Critical voices claim that antipsychotics, and psychotropic medication in general, are sometimes prescribed to persons with dementia with 'the only aim to dampen the activity without considering the cause' (Melin & Olsen, 2006, p. 115).
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LPS-induced inhibition of AMPK dampens the activity of these pathways, which is useful to highly activated cells as they need to boost biosynthetic pathways to produce inflammatory mediators.
It also helps reduce inflammation associated with lesions, thereby dampening the activity of factors in the tissue microenvironment that facilitate tumour development.
Because of the heterogeneity in global warming, that is, high latitudes tend to warm faster than low latitudes, the meridional temperature gradient and air pressure gradient are reduced, dampening the activity of atmospheric circulation, resulting in surface wind stilling (Vautard et al. 2010).
Now, by dampening the activity of a small group of neurons deep within the mouse brain, researchers have produced cognitive deficits similar to those found in those with schizophrenia, a discovery that they say could potentially lead to new treatments for the disorder, which affects roughly 24 million people worldwide.
External stimuli act on this interaction and shift the balance between synthesis and removal of matrix components in order to facilitate neuritic growth by locally dampening the activity of inhibitory cues.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com