Sentence examples for damaging score from inspiring English sources
10, 11 SIFT and Poly Phen which predict the function of non-synonymous variants (http://genetics.bwh.harvard.edu/pph/), also revealed that the p.P19S mutation "probably" damages the function of the NDUFA1 protein (damaging score, 0.956).
For the remaining variants, PolyPhen-2 was used to identify variants causing deleterious effects in the affected genes [probably damaging score: 0.909-1 0.909-1ly damaging score: 0.447 - 0.908; Benign score: 0 - 0.446; HumVar score: [ 18].
Genes are only retained for further analysis if the predicted damaging score for the variants exceeds that seen for 99%% of the 1000 Genomes dataset.
Interestingly, SNP rs14290671 on GGA23 is a missense variant located in the GNL2 (guanine nucleotide binding protein- like 2 (nucleolar)) gene, which causes a transformation from phenylalanine to cysteine, and the SIFT [ 26] score is equal to 0.06, which is close to the damaging score 0.05.
ATHENS — An earthquake with a preliminary magnitude of 6.5 rattled southern Greece on Sunday, killing two people, injuring dozens more and damaging scores of homes, officials said.
Puebla State Secretary Valentin Meneses said the explosion injured 52 people as well as destroying 32 houses and damaging scores more in San Martin Texmelucan - a small community about 80km (50 miles) east of Mexico City.
YANGON, Aug 24 (Reuters) - A powerful earthquake shook central Myanmar on Wednesday, killing at least three people including two children, and damaging scores of centuries-old Buddhist pagodas around the ancient capital of Bagan.
No damaging scores were observed for the additional 5 intronic SNPs located within 30 bp of exon-intron boundaries.
PolyPhen-2 values range from 0 to 3.37: variants with scores ≥ 2 were considered as "probably damaging," scores between 1.50 and 1.99 indicated a "possibly damaging," variant and scores 0 to 1.49 were considered as benign variants.
PolyPhen and SIFT predicted that this substitution was respectively "probably damaging" (with score of 0.999) and "deleterious" (with score of 0.01).
The reduction in damaging behaviour and the lower tail damage scores of pigs on straw clearly point out the potential of substrate to improve pig health and welfare.
