Sentence examples for damaging effect for from inspiring English sources

The software predicted a damaging effect for all four missense mutations, the fifth being a 1 bp frame shift deletion.

PolyPhen-2 predicted a "probably damaging" effect for the two mutations, with scores of 0.999 and 1.0, respectively (Table 1).

Although PolyPhen-2 predicted probably damaging effect for this mutation, no conformational changes of the mutant protein were shown by PSIPRED program (Table 1).

Of note, in silico analysis using several tools (Mutation Taster, PolyPhen-2, SIFT, Provean) predicted a damaging effect for all of them.

Because each variant can have multiple consequences, Olorin automatically selects and displays only the most damaging effect for each variant, showing the remainder via a popup box.

In this microfluidic format of the assay, the membrane damaging effect of a given compound, for example, a drug candidate from a combinatorial library or a natural source, can be determined by using only a few microliters of sample material (10 μl in the system described here) and a minimum processing time (two minutes per sample/lane).

Hepatocytes may be particularly prone to damaging effects by NK cells for two reasons: (1) the hepatocytes express relatively low levels of MHC class I molecules which inhibit NK cells (Ochi et al. 2004) and (2) the liver contains a specific subpopulation of NK cells lacking Ly-49 inhibitory receptors which recognize MHC class I (Ochi et al. 2004).

A permanent chromosome damaging effect has been additionally suggested for microcystins by studies that showed an induction of micronuclei (MN) in vivo [ 28] or in vitro [ 37].

The longer the booze stays in your system, the more alcohol builds up in your bloodstream, which puts you at greater risk for damaging effects.

The EDX results indicated that oxidative wear was one of the crucial damage effects for the tube sample under the impact wear condition.

Elasto-plastic behaviour with damage effect was assumed for the timber material, linear elastic isotropic model was used for the CFRP, and a cohesive model was used to represent the interaction between two adherent surfaces (CFRP and timber).