Sentence examples for damaging compound from inspiring English sources

However, elevated levels of endogenous p53 did not result in up-regulation of p21 in the presence of the DNA damaging compound cisplatin (CDDP) (Figure 1A, right panel, compare lanes 2 and 4 to lanes 6 and 8), indicating that the response of the p53 pathway to DNA damage had been compromised [26], [38].

Moreover, the combined treatment of nutlin-3, together with the DNA damaging compound doxorubicin, boosted p53 levels and restored normal transcriptional activity.

Data obtained with the activation of the DNA damage checkpoint by etoposide provide an example of detectable modification of cell cycle suggesting that Capan-2 Fucci expressing spheroid models could be used to detect or to investigate the effect of a novel DNA damaging compound.

DR5 is induced by DNA damaging compounds in malignant gliomas, including LN-229 [ 40].

This study opens up avenues for identifying new DNA damaging compounds from deep-sea bacteria.

Generally, platinum compounds are DNA damaging agents, and proliferating cancer cells are more prone to being killed by these DNA damaging compounds [8].

Alkylating agents are a structurally diverse group of DNA damaging compounds which form adducts at ring nitrogen (N) and extracyclic oxygen (O) atoms of DNA bases [ 1].

Yasir Arafat, speaking from his badly damaged compound in the West Bank city of Ramallah, said he welcomed Israel's support for the road map.

He spoke to journalists outside his badly damaged compound in Ramallah in the West Bank after meeting with the Latin patriarch of Jerusalem, the Rev. Michel Sabbah.

Israel has confined Mr. Arafat, the Palestinian leader, to his badly damaged compound in Ramallah on the West Bank for most of the last three years.

Mr. Sharon has been somewhat vague on whether he would be willing to act against the Palestinian leader, Yasir Arafat, who has been confined to his badly damaged compound in Ramallah, just north of Jerusalem, for the past two years.