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Dendroctonus bark beetles (Curculionidae: Scolytinae) are natural agents of change in forest ecosystems, as they parasitize and kill damaged, stressed or old pine trees (Fam: Pinaceae), thus promoting natural regeneration of the forest.
As previously discussed, the man is damaged, stressed, and wants to get the hell out of dodge and after all he's seen?
Innate immune cells are found in every tissue type, poised to respond immediately to damaged, stressed, or infected host cells.
These cells patrol the body's organs and tissues in an effort to immediately respond to pathogens and damaged, stressed or otherwise abnormal host cells.
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Hormesis B causes stresses including damaging stresses.
If aging is caused by damage, then damaging stresses would accelerate aging.
The advice we're given is to reduce the amount of damaging stress in our lives.
Importantly, it has been shown that in mammal cells the JNK cascade converts damaging stress stimuli in a sensitive switch-like response.
The stabilization and activation of p53 in response to DNA damaging stress result from post-translational modifications (phosphorylations) in p53 and MDM2 that disrupt their interaction [ 3].
Upon mechanical challenge, an acute inflammatory cascade is immediately activated in damaged or stressed tissues [62], [63].
Activation of p53 induces cell cycle arrest, apoptosis, or DNA repair when cells are damaged or stressed [22].
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CEO of Professional Science Editing for Scientists @ prosciediting.com