Sentence examples for damaged pathway from inspiring English sources

The same agonist also reduces proteinuria in diabetic nephropathy [ 132], in part by interrupting the damaged pathway initiated by lysoglobotriaosylceraminde in podocytes.

Knowing the damaged pathway can help understand the interaction between the different DNA repair systems and find candidate targets for therapy through the use of the mechanism known as synthetic lethality [ 4].

Such a model could furthermore help identify drugs that would repair damaged pathways or even cause new ones to be formed.

This supports the role of PKC δ in DNA damaging pathways, whereas alternative apoptotic pathways maybe recruited to facilitate cell death in response to other stimuli.

Both insulin resistance and hyperglycemia lead to oxidative stress and mitochondrial overproduction of superoxide and activate damaging pathways leading to diabetes complications.

Both hyperglycemia and/or insulin resistance can lead to oxidative stress and mitochondrial overproduction of superoxide and activate damaging pathways leading to diabetic micro- and macrovascular complications.

The model, for example, does not include the DNA damage pathway, signaling through other RTKs such as FGFR and EGFR, the Wnt pathway, and the TGFβ pathway.

NEDDylation has been shown to participate in the DNA damage pathway, but the substrates of neural precursor cell expressed developmentally downregulated 8 (NEDD8) and the roles of NEDDylation involved in the DNA damage response (DDR) are largely unknown.

A second anti-oxidative damage pathway in Archaea involves DPS-Like protein (DPSL).

Adding exogenous NPRL2 to cisplatin treatment induces three key events in the DNA damage pathway.

It is composed of the activity scores of six pathways: Trka Pathway, DNA Damage pathway, Ceramide Pathway, Telomerase Pathway, CD40L Pathway and Calcineurin Pathway.