Exact(20)
His research focuses on axonal pathophysiology in diseases and injuries of the central nervous system (CNS) and on transplantation based mechanisms to repair and protect the damaged CNS.
Olfactory ensheathing cells (OECs) have become a popular candidate for the transplant-mediated repair of the damaged CNS.
Increasing interest has focused on the development of innovative therapeutic methods that aim to regenerate damaged CNS tissue by taking advantages of recent advances in stem cell and neuroscience research [ 25, 26].
Free HA accumulates in the extracellular matrix of damaged CNS [43], [44] and may contribute to the inhibition of re-myelination and axonal regeneration during CNS repair due to its influence on neural stem/progenitor cell differentiation, astrocyte proliferation and migration, oligodendrocyte maturation and re-myelination, axon outgrowth and the onset of inflammation [45].
Of particular promise in that regard are stem cells, which could help repair damaged CNS structures.
Pathogenic B cell responses to the damaged CNS are one possible contributing factor.
Similar(40)
Damaged cells are either removed by the macrophages at rate k6 DM or by other mechanisms (unspecified) at the rate d D D. Equation (4) indicates that normal cells are replenished from regenerating fibers at the rate k4 R and are damaged at the rate k5 CN by the presence of specific CD8+ T-cells.
A bridge over the waterway was damaged, according to an email from CN spokesperson Emily Hamer.
Archeological collections provide an opportunity for studying and analyzing real life examples of aged CN, collection of spectra, enabling exploration of patterns of material use without damaging or removing original material from artefacts.
HMM estimates CNs.
After every anastomosis, the surrounding brain, all exposed cerebral arteries, and all exposed cranial nerves (CN) were systematically inspected and scored for damage (yes-no) by an observer, other than the surgeon.
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