Exact(14)
This suggests that the nucleoplasmic fraction of SLX4 is recruited to DNA damage tracks, where SIMs enable SLX4 to bind to SUMOylated proteins at damaged DNA.
And they must run them slower because extreme cold can freeze switches and damage tracks.
Recruitment of the GFP fusion proteins to MIR-induced DNA damage tracks was monitored in live cells.
FUS was previously shown to be rapidly recruited to UVA irradiation-induced DNA damage tracks in a PARP-dependent fashion17,18,19.
Independent studies demonstrated that FUS is recruited to DNA damage tracks by microirradiation (MIR) at wavelengths of 405 nm or 351 nm (UVA), respectively, in a PARP1-dependent manner presumably via interaction with PAR groups17,18,19.
To further dissect the role of FUS in this early oxidative DNA damage response, we examined the effect of FUS depletion on XRCC1 recruitment to MIR-induced DNA damage tracks.
Similar(46)
Both FUS mutants showed significantly reduced recruitment at the damage track (Fig. 7a, b, Supplementary Movie 1, 2 and 3).
A concept of phase space warping is used to develop new damage tracking feature vectors from measured time series through phase space reconstruction.
Google hopes that by offering free, high-quality music — giving consumers fewer worries about viruses or damaged tracks — it can cut into Baidu's lead.
Their lethal load and special construction made them so heavy, the paper said, that they damaged tracks, sparking a wave of complaints from over-worked railway workers to the Communist party central committee.
The war damaged tracks and facilities, but the nearly 10 miles of railway bridges were the most difficult to replace, said Narcis Dzumhur, general manager of the railway company in Sarajevo.
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