Mutations in germ cells can lead to spontaneous abortions, infertility or heritable damage to the offspring and possibly to the subsequent generations [5].
Maternal gestational cocaine abuse can cause damage to their offspring.
A new ethical concern specific to these IVF techniques is that rather than just affecting the single offspring, any damage to the transferred DNA would be passed on through the sperm or egg into a future generation.
It is likely that the DNA in the sperm is also damaged, meaning harm can be passed to offspring.
Once taken off the drug, the males reverted to normal sperm counts, sufffered no permanent damage to their reproductive organs, and sired typical numbers of healthy offspring.
With one exception [ 12], published reports to date do not support a hypothesis of major damage to reproduction or of deleterious effects on the health of their offspring.
There is widespread fear of damage to the reproductive system, with implications for fertility problems and adverse effects on offspring.
One possibility is that FoxO functions to reduce damage to interstitial stem cells over the potentially long life of an individual Hydra and its asexually produced offspring.
In this situation, informed consent of the offspring receiving the undesirable effects cannot be obtained, and there is uncertainty over who takes liability for genetic damage to be passed down several generations (Rodriguez, 2016).
Serious damage to reservoirs.
