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As the damage progresses, microglia undergo progressive changes, including altered expression of cell surface markers and inflammation-related genes, process retraction and the acquisition of an ameboid morphology, cell body migration, and increasing phagocytic ability [2].
Even with low disease activity, damage progresses and only sustained remission is capable of abrogating progression of joint destruction [ 3].
For small distances the damage progresses quickly, while three stages can be found for the control samples and for the distance of 20 mm.
A prototype three-story steel dual-core self-centering braced frame (DC-SCBF) was designed, and its full-scale first-story one-bay DC-SCBF was tested to (1) validate the system response, (2) study force distributions in framing members as damage progresses in the DC-SCB, beam or columns, and (3) investigate the repair and replacement characteristics of the frame.
In the spleen, lungs and liver, viable fungi are gradually cleared even while infection damage progresses in the kidneys [10], [11].
BI-1 expression is down-regulated as liver damage progresses.
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Sally Hunt, general secretary of the University College Union (UCU), said: "Cost does matter and there is a very real danger that raising tuition fees combined with the ending of maintenance grants will damage progress made by widening participation initiatives".
Higher education experts are concerned that the switch to a loan, just as universities are announcing plans to raise tuition fees beyond £9,000 a year, will damage progress in widening participation and lumber those who choose to go to university with even greater debt.
Investigators note that before breaking up on Feb. 1, the Columbia entered the atmosphere far west of the California coast, but held together until it was over Central Texas, a sign that the breach in the wing must have been small and that the damage progressed relatively slowly.
Damage progress in quasi-isotropic CFRP laminates under tensile fatigue loading is investigated microscopically.
The local damage progress near the crack tip is also investigated in details.
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