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Since CNTs exhibit great tensile strength, mechanical damage of tissues may be induced by piercing effects.
Although each type of NPs was found to cause toxic damage of tissues, larger particles were less toxic, probably, due to their lower penetration capacity [113].
Decreased enzyme activity of the antioxidant system and increased levels of free radicals may have important roles in the damage of tissues observed in the disease period.
It is much debated, whether TCDD is carcinogenic only at high doses which also cause toxic damage of tissues.
A number of studies suggested that a major result of Zn deficiency can be an increase in oxidative damage of tissues [42].
The damage of tissues and cellular components is the result of oxidative stress, due to the oxygen-free radicals and other reactive oxygen species [ 34].
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Albumin (ALB) was assayed as one parameter of damage of tissue or inflammation.
If the buffering capacity of the surfactant layer toward phosgene is exhausted, direct contact and damage of tissue cannot be excluded.
In brief, lung inflammation and damage of tissue were analyzed with respect to the following parameters: surface with pneumonia, necrosis and/or formation of abscess, interstitial inflammation, endothelialitis, bronchitis, edema, thrombus formation, and pleuritis.
Our method overcomes the loss of sections and damage of tissue and cell morphology, and allows parallel immunostaining in multiple colors, co-immunostaining with fluorescent proteins in transgenic fish lines and in combination with whole mount in situ hybridization.
Neutrophils are short-lived multinuclear white blood cells that have a profound role in ECM degradation and are responsible for several diseases characterized by severe damage of tissue structure [ 51- 53].
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