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Hence, rods may be more likely to be damaged and potentially resorbed by damage mediated remodeling.
Tissue damage mediated by neutrophils can be initiated by complement fragments, notably C5a, which are potent stimulators of neutrophil superoxide production and adherence to coronary artery endothelium.
Glutathione S-transferases, enzymes that prevent cells from damage mediated by oxidant and electrophilic carcinogens, may be early critical determinants of carcinogenesis.
Prolonged hyperoxia causes lung injury and respiratory failure secondary to oxidative tissue damage mediated, in part, by the superoxide anion.
The consequences of these oxidative processes during sepsis may be ongoing cell damage mediated by reactive oxygen and nitrogen oxide species that culminates in multisystem organ failure.
Certain phytomedicines have been reported to possess antioxidant capability, and are thus proposed to be protective against cell damage mediated by ROS.
Similar(20)
Cellular perception of these DNA adducts leads to the activation of DNA-damage mediated apoptotic pathways.
The hydrophilic Fe(II) complex entered cancer cells through transferring receptor (TfR -mediated endocyTfR -mediatedanslocatendocytosisnucleus, where they induced S phand cell cycle arrestranslocatediggering DNA damage-mediatod p53 pathway.
a DNA damage-mediated p53.
Furthermore, AgNP-induced apoptosis was found dependent on the overproduction of reactive oxygen species (ROS) and affecting of MAPKs and AKT signaling and DNA damage-mediated p53 phosphorylation to advance HePG-2 cells apoptosis.
Platinum-based agents, such as cisplatin and carboplatin, are toxic to dividing cells due to the formation of DNA adducts that result in double strand breaks, activating DNA damage-mediated apoptotic signals [2].
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