While the cost to truckers and feasibility will determine which technology succeeds commercially, reducing environmental and human health damage is their primary purpose: and determining which one does that best is not simple.
Alkali sensitivity damage is the primary damage mechanism in low permeability reservoirs and strongly influences rock permeability.
Scratch-induced damage is a primary limitation in the suitability of brittle glasses for this purpose.
Whether NE-mediated damage is a primary cause of these persistent infections or whether other elements in the CF lung environment also contribute to impaired clearance of these specific bacteria remains a matter of debate [79, 80].
Kidney damage is the primary consequence, but most toxicity data are from exposures in occupational settings or severely polluted areas.
The prevailing view is that alveolar damage is the primary pathology leading to acute respiratory distress, multiple organ dysfunction syndrome and death [ 3].
Prevention of joint damage is a primary goal of FVIII replacement therapy that can be administered on demand to stop bleedings or prophylactically to prevent them.
Experimental models have also suggested that brain microvasculature damage is the primary event in the development of late radiation-induced brain injury (Coderre et al, 2006).
Importantly, if H2A.Z is not deposited into chromatin in the vicinity of DNA damage in the first place, then INO80 and ANP32E are no longer required for wild-type levels of RAD51 foci or SCE formation in these assays, indicating that the removal of H2A.Z from chromatin in the vicinity of DNA damage is their primary function in HR.
CFTR is expressed in the membrane of the intrahepatic and extrahepatic biliary canaliculi cells and in the gallbladder epithelial cells, but it is not present in the hepatocytes, so the damage in this condition is primary biliary and causes increased bile viscosity.
The sample size of the study has been determined in order to detect statistically significant differences in the early effect biomarkers, that is, primary DNA damage and MN, between children living in towns with high and low air pollution levels.
