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However, Fas-mediated liver and chondrocyte damage is a serious problem in its clinical application.
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Building damage by earthquake action is a serious problem; in this regard, (Rachana and Mohod 2012) studied seismically deficient structures by carrying out the pushover analysis of frame structures using structural analysis and programming software.
Damage caused by underground coal mining is a serious problem in mining areas in China; therefore, studying and obtaining the rules of ground movement and deformation under different geological conditions is of great importance.
Corrosion is a serious problem in RC structures which damage the steel bar-concrete interface thus degrading bond strength and ultimately shortening the service life.
Wax deposition is a serious problem in the Petroleum Industry that results in the formation damage, flow restrictions and decreased production rate.
Corruption is a serious problem.
British scepticism is a serious problem.
Unemployment is a serious problem, yes.
Moreover, water pollution is a serious problem.
So this is a serious problem".
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