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Recently, the SNEV complex has been connected to DNA damage checkpoint signaling pathways.
PLK1 is identified as a modulator of DNA damage checkpoint.
DNA End Resection, Homologous Recombination and DNA Damage Checkpoint Activation Require CDK1.
Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes.
This is the biochemical demonstration of a DNA damage checkpoint that targets Cdc7/Dbf4 protein kinase.
Most importantly, we show that pRB is a critical component of this DNA damage checkpoint.
The DNA damage checkpoint pathways sense and respond to DNA damage to ensure genomic stability.
Ira, G. et al. DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1.
Townsend, K. et al. Mediator of DNA damage checkpoint 1 (MDC1) regulates mitotic progression.
Mahajan, K. hPso4/hPrp19: a critical component of DNA repair and DNA damage checkpoint complexes.
Goldberg, M. et al. MDC1 is required for the intra-S-phase DNA damage checkpoint.
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