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This suggests a cellular state of forced passage through G2 checkpoint despite large DNA damage, a scenario that may produce mitotic catastrophe.
As resident brain macrophages, microglia function as sentries, but when activated they can mediate tissue damage, a scenario considered for several CNS inflammatory disorders (10, 15, 27).
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Based on the level of muscle damage, a possible scenario was exhaustion of the satellite cell population as a result of continuous cycles of regeneration, as has been proposed for DMD patients.
The former tells us the cost of climate damages in a scenario where we also take significant steps to slow global warming.
Furthermore, significant degradation in material performance can be experienced with minimal visual indication of damage being present, a scenario termed Barely Visible Impact Damage (BVID).
Building damage due to a scenario earthquake in Metro Manila, Philippines is estimated based on seismic performance of the buildings evaluated by local experts' judgments.
A single span steel bridge was used to simulate a damage scenario by adding and removing mass through a 20.2 kg bucket connected to the laboratory crane while the bridge was subjected to low amplitude noise excitation (Fig. 4).
The scientific literature presents various methodologies for generating a damage scenario for built-up areas impacted by an earthquake (Erdik et al. 2010), each method combines variables in different ways.
Finally, the study proposed a damage scenario to explain the failure of the on-axis loaded specimens which still needs to be supported by X-ray CT scans.
Moreover a damage scenario is proposed, reduced to two phases in post-impacted fatigue behaviour, instead of three phases for non impacted specimens.
A simple-supported 12 bay steel bridge (Fig. 9) was used to simulate a damage scenario by the removal of mass while the structure is being excited by low amplitude white noise.
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