Suggestions(1)
Exact(7)
For these products, the longer dosing interval regimens produced similar BMD increases from baseline to the corresponding daily formulations.
The benefits of oral alendronate, risedronate, and ibandronate on fracture risk reduction for patients with postmenopausal osteoporosis were established in studies of daily formulations of each product.
Extended-release (twice daily) formulations of valproic acid or carnitine supplementation are the proposed two therapeutic strategies in order to reverse hyperammonemia.
Monthly and daily formulations increase the likelihood that patients may delay or miss treatments, which can result in testosterone breakthrough and potentially compromise tumor control and increase symptom progression.
Subsequent studies compared the efficacy of longer dosing interval regimens of these products with the corresponding daily formulations in terms of BMD increase, which is associated with reduced fracture risk.
Treatment with the shorter-acting variations such as 1-month depot and daily formulations presents more opportunities for patients to delay or altogether miss treatments, which can result in testosterone breakthrough and potentially deleterious effects on tumor control and symptom progression.
Similar(53)
Transdermal films of duloxetine hydrochloride have been successfully formulated as once daily formulation by solvent evaporation technique.
The motive of our study was to formulate and characterize the transdermal patches of duloxetine hydrochloride in order to explore the feasibility of this route of administration to provide a once daily formulation for the drug.
Against strains with amoxicillin MICs of 4 mg/L, amoxicillin/clavulanate 2000/125 mg twice daily was significantly more effective than the conventional 875/125 mg twice daily formulation, azithromycin and levofloxacin, even though all levofloxacin MICs were ≤ 1 mg/L.
In vivo studies were carried out for the optimized formulation with 12 healthy human volunteers and obtained pharmacokinetic parameters were compared with the marketed once daily formulation, "Zanocin OD".
Following infection with S. pneumoniae strains with amoxicillin MICs of 8 mg/L, the amoxicillin/clavulanate 2000/125 mg twice daily formulation was more effective than the conventional amoxicillin/clavulanate formulations of 875/125 mg twice daily and three times daily and 1000/125 mg three times daily, and had similar or better efficacy than azithromycin and levofloxacin, depending on the strain.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com