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There is at present substantial evidence for the involvement of the DA system in the pathophysiology of depressive-like disorders4.
Despite inducing shared behavioral maladaptations, these models are underpinned by different, and sometimes opposite, cellular changes within the DA system.
However, with activation of the DA system, increased DA transmission would attenuate most afferent hippocampal and amygdaloid input.
A new data acquisition (DA) system has been developed for the MAST experiment at Culham.
Based on its connectivity with VTA GABA interneurons, the MHb, LHb, IPN, and RMTg, the mPFC provide strong inhibitory regulation of the mesolimbic DA system (Figure 4).
This would result in an enhanced sensitivity of the DA system to a moderate social stress, and the appearance of social aversion.
Recent studies have shown that this mesocortical DA system differs from other DA systems (such as the nigrostriatal and mesolimbic DA systems) in terms of drug responsiveness.
The mPFC can also inhibit mesolimbic dopaminergic activity through a number of other pathways, with the corticohabenular tract being potentially critically important in regulating the mesolimbic DA system.
The DA system is distributed across a number of computers with a DA process for each distinct diagnostic system.
A computer-based dynamic assessment (DA) system developed for use in an undergraduate fluid mechanics course is presented.
GDNF has substantial effects on the nigrostriatal dopamine (DA) system of young adult, aged and lesioned animals.
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