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Abbreviations: Sham unstretched cells under normocapnia, Normo high cyclical stretch with normocapnia, HCA high cyclical stretch with hypercapnia, MA high cyclical stretch with metabolic acidosis, BHC high cyclical stretch with buffered hypercapnia.
Abbreviations: Normocapnia-Sham unstretched cells with normocapnia, Normocapnia-Stretch high cyclical stretch with normocapnia, HCA-Sham unstretched cells with normocapnia, HCA-Stretch high cyclical stretch with hypercapnia.
We sought to enhance the viability and functional maturation of cardiac tissue constructs by cyclical stretch.
Surprisingly, we found that TGFβ induced ASMA expression was reduced when cells underwent cyclical stretch compared to static cells.
Isolated human annulus fibrosus (AF) and nucleus pulposus (NP) cells were exposed to HMS (20% cyclical stretch at 0.001 Hz) on high-extension silicone rubber dishes coupled to a mechanical stretching apparatus and compared to static control cultures.
Mechanical deformation, either by static or cyclical stretch, increases the rate of HA production in both intact joints (14, 29) and cultured rabbit intimal synoviocytes (52), demonstrating that synoviocytes exhibit a mechanosensitive response.
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hESC-CMs seeded onto gelatin-based scaffolds underwent cyclical stretching.
We measured passive muscle tension during cyclical stretching (20%) around L0 (sarcomere lengths of 2.2 μm) in fiber bundles extracted from cruralis and plantaris muscles.
To investigate the longevity and cumulative impact of multiple sessions of passive, cyclical stretching of the digits on hand function in subacute stroke survivors.
Twenty years ago, oceanographers had gathered enough evidence to conclude that the march of ice ages over the last million years was paced by the cyclical stretching and squeezing of Earth's orbit around the sun, which would have altered how sunlight fell on the planet's surface.
Cyclical stretching forces theoretically can promote bacterial growth in human alveolar cells and predispose patients to pneumonia, and thus the use of lung protective ventilation theoretically could reduce the incidence of VAP.
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