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In particular, we have developed a cyclic acetal biomaterial (EH network) based on 5-ethyl-5- hydroxymethyl -β,β-dimethyl-1,3-dioxane-2-ethanol diacrylate.
In order to address this concern, we proposed to develop a hydrogel based on a cyclic acetal unit that produces diols and propanals upon hydrolytic degradation.
This work establishes that an EH network, a degradable cyclic acetal biomaterial, can function as a scaffold for skeletal muscle engineering.
A reaction scheme involves the formation of cyclic acetal ethers between GVL and glycerol was proposed to explain the product distributions in the one-pot synthesis of 1,3-PDO and GVL.
A cyclic acetal of dimethyl l-tartrate (dimethyl 2,3-di-O-methylene l-threarate, Thx) was used as comonomer of dimethyl terephthalate (DMT) in the polycondensation with 1,6-hexanediol (HD) in the melt.
In particular, we proposed the fabrication of hydrogels formed by the free radical polymerization of two diacrylate monomers, 5-ethyl-5- hydroxymethyl -β,β-dimethyl-1,3-dioxane-2-ethanol diacrylate (EHD), a cyclic acetal having two acryl groups, and poly(ethylene glycol)diacrylate (PEGDA).
Similar(48)
LA promoted the hydrogenolysis of glycerol over Ru/C catalyst, in which LA catalyzed dehydration of glycerol into acetol (precursor of 1,2-propanediol (1,2-PDO)), and glycerol acetalization with the hydrogenated GVL into cyclic acetals, resulting in the formation of 1,3-PDO.
Cyclic acetals were used to replace the conventional amines in bimolecular photoinitiating systems.
The mixtures of benzophenone derivatives and cyclic acetals were used to initiate the UV photopolymerization of 1,6-hexanedioldiacrylate (HDDA).
The results showed that the addition of cyclic acetals greatly increased the rate of polymerization (Rp) and final double bond (DC) of HDDA.
Cyclic acetals based biomaterial without acidic products during hydrolytic degradation is a promising candidate for tissue engineering applications; however, low hydrophilicity is still one limitation for its biomedical application.
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