The use of the TETA/Cu reversible system described here could be used to trigger several subsequent cycles of gene expression/silencing in a cheap, energy-efficient way.
Thus, for detection of lunar cycles of gene expression, comparison among lunar days was done independently for the 1400 h and 2200 h sample times.
At the core of the circadian clock is a set of transcription factors that form transcription-translation feedback loops that maintain cycles of gene expression over a 24 h period.
Consistent with this idea, we have also discovered that basal Ptetbi activity is essential for achieving multiple cycles of gene inactivation by Dox and re-activation upon Dox withdrawal in tTA-activator/Ptetbi-responder mice [9], [21], [35].
Most genes belong to gene families which are derived through consecutive cycles of gene duplication.
There is no indication that the whole tissue is undergoing dynamic cycles of gene expression.
Most genes belong to gene families, which have emerged through consecutive cycles of gene duplications during evolution [ 1].
In non-human animals, circadian cycles of gene expression have been demonstrated in the blood, brain, liver, kidney, skeletal muscle, and heart 33– 33.
Comparisons of target and control genes are no longer relevant at the single-cell level, as cycles of gene expression burst and degradation are known to occur across all genes, including housekeeping or control genes.
When demes have different environmental conditions, resulting in different values of u, b or the cost to a plant of being diseased (s), the periods of the cycles of gene frequencies differ (13).
