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Current results of the analyses for all of the cycles are summarized in Part II.
Pregnancy outcomes in 455 consecutive IVF cycles are summarized in Figure 2. As the figure demonstrates, norm women experienced the highest pregnancy rates (38.6%), a rate significantly higher than in het-norm/low patients [22.2%; OR 0.84 (95% CI 0.74 to 0.96; Wald 6.9; df = 1; P = 0.009)].
The cumulative results of the six cycles are summarized in Table 1.
Treatment-emergent AEs (TEAEs) over all cycles are summarized in supplementary Table S2, available at Annals of Oncology online.
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The incidence of adverse events (AE) by dose group at all cycles is summarized in Table S2.
Characteristics of the women and IVF cycles were summarized using means, standard deviations, and percentages, as appropriate.
Strategies based on (engineered) microbes that potentially can contribute to this cycle are summarized.
The populations of the various phases of the cell cycle are summarized in the Supporting Information.
Methyl side chain assignments for several intermediates of the hDHFR major enzymatic cycle are summarized in Table S1 of the Supporting Information.
The time versus serum concentration curves for each patient are shown in Figure 2 and the PK parameters related to each dose and treatment cycle are summarized in Table 3.
The sequence leading to the formation of urea, commonly called the urea cycle, is summarized as follows: Ammonia, formed from glutamate and NAD+ in the liver mitochondria (reaction ), reacts with carbon dioxide and ATP to form carbamoyl phosphate, ADP, and inorganic phosphate, as shown in reaction.
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