These combined effects result in a vicious cycle of tissue destruction and inflammation, explaining the rapid onset and lethal outcome of this type of pneumonia," Bowden said.
The presence of periodontal pathogens in diabetic patients can initiate a cycle of tissue destruction and impaired wound healing which lead to tooth loss [ 47].
This incessant cycle of tissue injury and repair is presumed to be a major contributor to the development of lung cancer [ 75, 84- 86].
These observations are consistent with the origin of 2HA by selection from a regenerated plant that had passed through a cycle of tissue culture [ 1, 28] suggesting that the epigenetic changes in culture can be fixed in regenerated plants.
Indeed, while persistent and chronic inflammation promotes a vicious cycle of tissue damage and carcinogenesis, an effective acute inflammation is key to the eradication of pathogens (Fox and Wang, 2007; Round and Mazmanian, 2009).
The effects are diverse, but when the homeostatic balance is disturbed, reactive oxygen species typically conserve a vicious cycle of tissue injury, characterized by cell damage, cell death, and inflammation.
Our observations are consistent with the origin of 2HA by selection from a regenerated plant that passed through a cycle of tissue culture [ 1, 31] and suggests that epigenetic changes in culture directed at specific genes can be fixed in regenerated plants.
Nevertheless, our data suggest that Mcm-2 may offer advantages over Ki67 as a marker of the cell cycle 'state' of tissues.
The pathology of inflammatory periodontal disease progresses through cycles of tissue destruction, followed by periods of quiescence and tissue repair.
Three cycles of tissue disruption were performed using the Mini-Bead Beater Type BX-4 Cell Disrupter (Glen Mills Inc., Clifton, NJ, USA), for 30 s each, at 5000 rpm.
