Sentence examples for cycle of highly from inspiring English sources

With the introduction of the 5HT3 antagonists in the 1990s and the combination with dexamethasone, complete acute emesis protection became possible in 70% of patients receiving a first cycle of highly emetogenic chemotherapy.

A cost-consequence study found that the costs of an aprepitant-containing regimen were $US536 154 compared with $US238 982 for standard antiemetic therapy in a hypothetical cohort of 1000 patients receiving a single cycle of highly emetogenic chemotherapy (Bell et al. 2004).

NEPA, an oral fixed-dose combination of netupitant, a highly selective NK1 receptor antagonist (RA), and palonosetron (PALO), a distinct 5-HT3 RA, was shown to be superior to PALO in preventing chemotherapy-induced nausea and vomiting after a single cycle of highly (HEC) or moderately (MEC) emetogenic chemotherapy in recent trials.

A cost-consequence study that included costs for aprepitant plus standard antiemetics for a hypothetical group of 1000 patients receiving a single cycle of highly emetogenic chemotherapy concluded that savings in overall direct medical costs would offset 58.7% (range 20 80%) of the incremental cost of adding aprepitant (Bell et al. 2004).

His treatment was to be six cycles of highly toxic chemotherapy followed by radiation.

Compared with patients who received standard therapy alone (a 5-HT3 antagonist plus dexamethasone), those who received aprepitant in addition to standard therapy had consistently better antiemetic protection that was well maintained over multiple cycles of highly emetogenic chemotherapy.

We conclude that the anti-emetic efficacy of a 5HT3 antagonist plus dexamethasone is not maintained over multiple cycles of highly emetogenic chemotherapy, and that the acute emesis protection is adversely influenced by protection failure in the delayed emesis phase.

Aprepitant (Emend) is approved for use with other antiemetic drugs to prevent CINV in patients receiving initial and multiple cycles of highly and moderately emetogenic chemotherapy (Anon. 2006), based on the evidence from RCTs.

In this multinational, phase III study, the safety and efficacy of NEPA, a convenient, fixed-dose antiemetic combination of netupitant, a highly selective NK1 receptor antagonist (RA), and palonosetron, a distinct 5-HT3 RA, were evaluated over multiple cycles of highly and moderately emetogenic chemotherapy.

Taken together, these results show that elevated DDX21 expression is required in order to maintain the viability and cell cycle progression of highly proliferative breast cancer cells.

Scève's Délie, objet de plus haute vertu (1544; "Délie, Object of Highest Virtue") is a poetic cycle of 449 highly organized decasyllabic 10-line stanzas (dizains), rich in imagery and Platonic and Petrarchan in theme and style.