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SCOPE: The study tests the metabolites of the methylation cycle in individuals with Down syndrome (DS) and applies a mathematical model in order to change this cycle by nutritional factors.
We recorded the EEG during the first sleep cycle in individuals not engaged in any systematic task: SSO activity was expected during the NREM sleep.
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Muslce contractions in the defecation cycle in individual worms were observed over a period of 10 min.
More work is needed to understand the basic dynamics and differences of human protein levels and its variation across the cell cycle in individual cells.
This analysis also failed to detect effect of cycle in individual PF+ Wernicke's aphasia cases (Supplementary Table 4).
The mice were housed under a 12-hour light/dark cycle in individual ventilated cages and maintained in a specific pathogen-free grade environment.
Rats were placed in a quiet, temperature- and humidity-controlled room (23 °C ± 2 °C and 60%% ± 5%%, respectively), and kept on a 12-h light, 12-h dark cycle in individual home cages with food and water available ad libitum.
Here, we used live imaging and quantitative, 4D image analysis to measure the sources of cell-size variability in the meristem and then used these measurements in computer simulations to show that the uniform cell sizes seen in the meristem likely require coordinated control of cell growth and cell cycle in individual cells.
Interestingly, dysregulation of the clock also appears to contribute to disturbances of the sleep-wake cycles in individuals with Alzheimer's disease.
For instance, mitochondrial dysfunction was suspected to underlie high levels in urine of 2-hydroxyglutaric and of Krebs cycle intermediates in individuals displaying agenesis of the corpus callosum (see Box 2) and severe neurodevelopmental problems (Edvardson et al., 2013).
Overall results support the conception of career adaptability as a self-regulatory resource that may promote a virtuous cycle in which individuals' evaluations of their resources to cope with the environment (i.e., career adaptability) shape their affective states, which in turn influence the evaluations of their job.
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