Sentence examples for cycle function from inspiring English sources

These studies illustrate the impact of altered glycolysis and TCA cycle function on brain functionality and neurodegeneration.

Clock and cycle function as binding partners and are required for 24-hour transcriptional cycling of the core-circadian clock [ 14].

The ratio of ornithine to citrulline, a marker of urea cycle function, was elevated at all postoperative time points compared with preoperative values, indicating decreased urea cycle function.

Owen, O. E., Kalhan, S. C. & Hanson, R. W. The key role of anaplerosis and cataplerosis for citric acid cycle function.

Mavri-Damelin, D. et al. Ornithine transcarbamylase and arginase I deficiency are responsible for diminished urea cycle function in the human hepatoblastoma cell line HepG2.

This process triggers mitochondrial fission (fragmentation) and disturbs Krebs cycle function e.g. by inhibiting the activity of 2-oxoglutarate dehydrogenase.

Genes transcriptionally upregulated through promoter hypomethylation during malignant progression to high-grade glioblastoma were enriched in cell cycle function, evolving in parallel with genetic alterations that deregulate the G1/S cell cycle checkpoint.

We propose that age-related disturbances in the Krebs cycle function induce stochastic epigenetic changes in chromatin structures which in turn promote the aging process.

As the field progresses, the importance of aberrant TCA cycle function in tumorigenesis and the potentials of applying small molecule inhibitors to perturb the enhanced cycle function for cancer treatment start to evolve.

Improved ciliary function and normal nasal cycle function were among other benefits purported from increased nasal airflow resulting from RME.

Therapeutically targeting the TCA cycle function in cancer is an attractive strategy to treat cancer and two strategies are currently being tested in the clinic.