Sentence examples for cycle dose from inspiring English sources
During the extended treatment period (after the first cycle) dose reduction was allowed if patient experience toxicities.
If two DLTs were observed in a single cohort during the first treatment cycle, dose escalation was stopped, and dose finding was continued at a lower level.
Strategies used by both studies to manage anemia, thrombocytopenia, and neutropenia associated with azacitidine treatment included delay of the next treatment cycle, dose reduction, and blood product transfusions.
This study demonstrates that intrapatient dose escalation based on toxicity in the preceding cycle dose, as practised in Group B, is feasible.
Results from a retrospective study suggest that regimens with an increased dose per cycle (dose intensity) of anthracyclines (Thor et al, 1998) are associated with an improved outcome only in women with HER2 overexpression.
As our mean administered per cycle dose of CDDP to the Internal carotid artery was as low as 48.0 (mg per cycle), our new strategy was also determined to be safe.
Cycle doses were 7.4 GBq injected in 30 min.
Cycle doses were 100 mCi in seven patients, 150 mCi in 14 and 200 mCi in the remaining 14.
We administered far higher doses of carboplatin than those used by Vieitez et al. [ 15], according to our preliminary phase I study [ 20] that led us escalating the cycle doses of carboplatin from 300 mg/m2 to 350 mg/m2.
Dose-dense treatment is defined by delivery of a maintained per-cycle dose or overall dose with administration of drug at shorter time intervals than is standard.
A single-center phase II trial by Blum et al increased the first-cycle dose of decitabine to 20 mg/m/day for 10 days, with cycle length reduced to 5 days if response was observed.
