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Thus, if a systemic vasculitis is suspected, positive CV criteria, even in the absence of positive serum cryoglobulins by initial testing, should warn the clinician of a possible CV, and repeated cryoglobulin testing is mandatory.
Likewise, the statistical evolutionary trajectory index with statistical significance for zebrafish data is given in Supplementary Table 2, where we filtered out genes by coefficient of variation (CV) criteria remaining 12,034 genes.
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As shown in Table 2, most measurements (75.56−100%) across laboratories and assays met the <20% CV criterion for intra-assay reproducibility.
Of note, none of the three sets of items comprising the CV classification criteria herein developed (positive answer to ≥2/3 validated questions, presence of ≥3/4 clinical features, or presence of ≥2/3 laboratory abnormalities) is absolutely needed for classification itself, since classification is possible with positivity for any two of the three questionnaire, clinical or laboratory items.
Candidates for Biovision.Nxt were selected on the strength of their CVs, using criteria prepared by program director Abigail Gemo in consultation with several young researchers associations.
By including the CV selection criterion, 52 probesets, representing 50 cartilage-selective genes were identified and added to the complete tally (Table 1, right), including 6 genes also identified using the U133A and U133B arrays (IRAK2, NRP2, WTAP, PITPNC1, AKR1C2, and PTK2).
We consider three procedures for selecting optimal penalty, namely cross-validation (CV), Akaike Information Criteria (AIC) and Bayesian Information Criteria (BIC).
The accuracy and precision were within FDA criteria (CV <15%) at all three validation levels (Table 1), precision expressed as% CV was between 11.9% and 31.8% for within-run and between 8.5% and 14.5% for between-run experiments.
The classification criteria for CV developed by comparing data in group A (CV) versus group B (positive serum cryoglobulins without CV) were then also tested by comparing group A versus group C (as a whole, or distinguishing C1 and C2).
Applicants for postdoc and more senior positions definitely require a good CV, because the selection criteria are as tough as in Europe or the U.S.
A uniform set of classification criteria for CV was needed.
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